RNA helicases

One of the possible ways to control malaria could be to discover inhibitors specific for the essential enzymes of malaria parasite like DNA / RNA helicases .

控制疟疾的一个可行的办法就是研制出通过阻断疟原虫生长有关的关键酶来抑制其生长的药物，比如通过阻断DNA/RNA解旋酶等。

The ATP dependent RNA helicases of the DEAD box family , involved in almost every cellular process of RNA metabolism , play many essential roles during cell development and growth in almost all organisms .

DEAD盒蛋白家族的ATP依赖性的RNA解旋酶类参与细胞内几乎所有的RNA代谢过程，在几乎所有生物的细胞生长发育过程中扮演着众多不可或缺的角色。

VASA protein is a member of the DEAD ( Asp-Glu-Alu-Asp ) box family of ATP-dependent RNA helicases and initially found as a component of germ plasm in Drosophila .

vasa基因编码DEAD-box家族成员中一种ATP依赖的RNA解旋酶，在果蝇中作为生殖质的组成成份被首次报道。

Malaria still remains a major health problem in many parts of the world . One of the possible ways to control malaria could be to discover inhibitors specific for the essential enzymes of malaria parasite like DNA / RNA helicases .

疟疾目前仍然是世界上许多地方的一个主要的健康问题；控制疟疾的一个可行的办法就是研制出通过阻断疟原虫生长有关的关键酶来抑制其生长的药物，比如通过阻断DNA/RNA解旋酶等。

RNA helicases Retinoic acid induced gene-I ( RIG - ⅰ) is a newly discovered pattern recognition receptor ( PRR ), acting as a cytoplasmic dsRNA receptor and inducer of IFN production , to activate antiviral immune responses .

RNA解旋酶维甲酸诱导基因-Ⅰ（RIG-Ⅰ）是新发现的细胞内重要的模式识别受体，能识别胞内的dsRNA进而诱导IFN的产生，激活特异性免疫而发挥抗病毒作用。

The DEAD-box RNA helicases is a big ATP-dependent RNA helicases family , which originates from a wide range of organisms ranging from prokaryotes , including viruses , to eukaryotes such as yeast , plants and animals .

DEAD-boxRNA解旋酶是一个依赖ATP的RNA解旋酶大家族，广泛地存在于从原核生物的细菌到真核生物的酵母、植物和动物中。